⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31146034 | 0.83 | NPC1 (0.33) | — | |
| SCHEMBL31145836 | 0.83 | NPC1 (0.33) | — | |
| SCHEMBL31146190 | 0.78 | MEN1 (0.35) | — | |
| SCHEMBL31146082 | 0.78 | MEN1 (0.35) | — | |
| SCHEMBL31146105 | 0.74 | NPC1 (0.31) | — | |
| SCHEMBL31146026 | 0.74 | NPC1 (0.31) | — | |
| SCHEMBL31146180 | 0.74 | NPC1 (0.43) | — | |
| SCHEMBL31146206 | 0.73 | P2RX7 (0.31) | — | |
| SCHEMBL31146196 | 0.73 | P2RX7 (0.31) | — | |
| SCHEMBL31146194 | 0.73 | P2RX7 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688748-A1 | QUINOLINONE AMIDE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024206339-A1 | QUINOLINONE AMIDE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2024-10-03 | — | — | WO | disclosed |