Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1318387 | 1.00 | MAPT (0.55) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| SCHEMBL30411778 | 0.98 | MAPT (0.52) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| SCHEMBL839316 | 0.98 | MAPT (0.52) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| Bromide SCHEMBL4616453 | 0.95 | MAPT (0.51) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| Hydrochloric Acid SCHEMBL4613932 | 0.95 | MAPT (0.50) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| Perchlorate SCHEMBL11816261 | 0.90 | MAPT (0.51) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| Sulfuric Acid SCHEMBL29073034 | 0.85 | MAPT (0.47) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| Sulfuric Acid SCHEMBL28557836 | 0.83 | MAPT (0.50) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| SCHEMBL4613852 | 0.82 | ALDH1A1 (0.61) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| Iodide SCHEMBL29498811 | 0.78 | MAPT (0.45) | MAPTKDM4EALDH1A1TDP1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118702692-A | Preparation method of benzothiazole tetrafluoroborate fluorescent dye | 苏州络森生物科技有限公司 | 2024-09-27 | — | — | CN | disclosed |