Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL31147096 | 1.00 | MAPT (0.55) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| SCHEMBL30411778 | 0.98 | MAPT (0.52) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| SCHEMBL839316 | 0.98 | MAPT (0.52) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| Bromide SCHEMBL4616453 | 0.95 | MAPT (0.51) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| Hydrochloric Acid SCHEMBL4613932 | 0.95 | MAPT (0.50) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| Perchlorate SCHEMBL11816261 | 0.90 | MAPT (0.51) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| Sulfuric Acid SCHEMBL29073034 | 0.85 | MAPT (0.47) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| Sulfuric Acid SCHEMBL28557836 | 0.83 | MAPT (0.50) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| SCHEMBL4613852 | 0.82 | ALDH1A1 (0.61) | MAPTKDM4EALDH1A1TDP1CYP2D6 | |
| Iodide SCHEMBL29498811 | 0.78 | MAPT (0.45) | MAPTKDM4EALDH1A1TDP1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 512 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025058566-A1 | ORALLY-DELIVERED PLATINUM PRO-DRUG AGAINST CISPLATIN-RESISTANT OVARIAN CANCER | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2025-03-20 | — | — | WO | claimed |
| CN-117603203-B | Ratio fluorescent probe and preparation method and application thereof | 德州学院 | 2024-04-12 | — | — | CN | claimed |
| CN-117603203-A | Ratio fluorescent probe and preparation method and application thereof | 德州学院 | 2024-02-27 | — | — | CN | claimed |
| US-20220153783-A1 | MITOCHONDRIA-TARGETING COMPOUND AND COMPOSITION COMPRISING SAME FOR TREATING OR PREVENTING AGING-RELATED DISEASES | FUSION BIOTECHNOLOGY CO., LTD. (KR) | 2022-05-19 | — | — | US | claimed |
| CN-107286151-B | Carbazole-based two-photon fluorescent probe and preparation method and application thereof | 安徽大学 | 2020-03-17 | — | — | CN | claimed |
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| EP-1432388-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2008-06-18 | — | — | EP | claimed |
| US-7374580-B2 | Dyeing compositions comprising A 1,2-indandione derivative | L'OREAL S.A. (FR) | 2008-05-20 | — | — | US | claimed |
| US-7367993-B2 | Dyeing compositions comprising at least one 1,3-indandione derivative | L'OREAL S.A. (FR) | 2008-05-06 | — | — | US | claimed |
| EP-1699427-B1 | AGENT AND METHOD FOR OXIDATIVELY DYING KERATIN FIBERS | WELLA AG (DE) | 2008-02-27 | — | — | EP | claimed |
| EP-0998256-A1 | USE OF DI- AND OLIGOACYLAROMATS FOR COLOURING FIBRES CONTAINING KERATIN | Henkel Kommanditgesellschaft auf Aktien (DE) | 2000-05-10 | — | — | EP | claimed |
| WO-1999019558-A2 | USE OF MALONALDEHYDE DERIVATIVES FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-04-22 | — | — | WO | claimed |
| WO-1999018917-A2 | AGENT FOR DYEING FIBERS CONTAINING KERATIN WITH A CONCENTRATION OF DEHYDROASCORBIC ACID CONTENT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-04-22 | — | — | WO | claimed |
| WO-1999018916-A2 | UTILIZATION OF ONIUM ALDEHYDES AND ONIUM KETONES FOR DYING FIBERS CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-04-22 | — | — | WO | claimed |
| WO-1999018914-A2 | APPLICATION OF INDANONES FOR DYING FIBERS CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-04-22 | — | — | WO | claimed |
| WO-1999004754-A1 | USE OF DI- AND OLIGOACYLAROMATS FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-02-04 | — | — | WO | claimed |
| EP-0873743-A2 | Use of benzylidene-ketones for dyeing keratinous fibers | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-28 | — | — | EP | claimed |
| EP-0873744-A2 | Use of heterocyclic carbonyl compounds for dying keratinous fibers | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-28 | — | — | EP | claimed |
| EP-0873745-A2 | Dyestuff for keratinous fibers | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-28 | — | — | EP | claimed |
| EP-0873746-A2 | Dyestuff for keratinous fibers | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153783-A1 | MITOCHONDRIA-TARGETING COMPOUND AND COMPOSITION COMPRISING SAME FOR TREATING OR PREVENTING AGING-RELATED DISEASES | TFAM, HSPA9, AIFM1 | ACHE 4070/4885MAPT 396/4885KDM4E 3680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.