Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3114748 | 1.00 | PTGS2 (0.48) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL3113710 | 0.94 | PTGS2 (0.47) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL13114176 | 0.85 | FAAH (0.39) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL3117630 | 0.84 | FAAH (0.45) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL3117626 | 0.84 | FAAH (0.45) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL30116363 | 0.83 | PTGS2 (0.59) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL12884181 | 0.83 | PTGS2 (0.64) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL31121783 | 0.83 | PTGS2 (0.47) | PTGS2FAAHPTGS1CXCR1CXCR2 | |
| SCHEMBL3118844 | 0.79 | PTGS2 (0.52) | PTGS2PTGS1LMNACYP2C9AKR1C3 | |
| SCHEMBL28531621 | 0.78 | PTGS2 (0.56) | PTGS2FAAHPTGS1CXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100255050-A1 | Polyethylene Based Bioactive Agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2010-10-07 | — | — | US | disclosed |
| WO-2009015274-A2 | POLYETHYLENE BASED BIOACTIVE AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-01-29 | — | — | WO | disclosed |