Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ESRRB | O95718 | 2/20 | 0.47 |
| ▸ | ESRRG | P62508 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15774565 | 0.87 | HPGD (0.62) | LMNAHPGDCYP2C19CYP2C9CYP1A2 | |
| SCHEMBL3438336 | 0.78 | HCAR3 (0.61) | LMNAHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL15992013 | 0.77 | PPARG (0.60) | MAPTLMNAHPGDCYP2C19CYP2C9 | |
| SCHEMBL15992290 | 0.76 | PPARG (0.58) | TP53LMNAHPGDCYP2C19CYP2C9 | |
| SCHEMBL2553688 | 0.74 | MEN1 (0.52) | TP53MAPTHPGDCYP2C19CYP2C9 | |
| SCHEMBL14800316 | 0.74 | MEN1 (0.54) | TP53MAPTHPGDMEN1KMT2A | |
| SCHEMBL16731537 | 0.73 | HPGD (0.59) | TP53LMNAHPGDMEN1KMT2A | |
| SCHEMBL3437993 | 0.72 | KMT2A (0.58) | TP53MAPTLMNAMEN1KMT2A | |
| SCHEMBL2939210 | 0.72 | FGFR1 (0.54) | TP53MAPTLMNAHPGDCYP2C19 | |
| SCHEMBL2937848 | 0.71 | HCAR3 (0.55) | TP53MAPTLMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118984827-A | GLP-1R modulating compounds | 歌礼生物科技（杭州）有限公司 | 2024-11-19 | — | — | CN | disclosed |