Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3438336 | 0.86 | HCAR3 (0.61) | MEN1KMT2APTGER4SMN1; SMN2HTT | |
| SCHEMBL6243442 | 0.82 | ALDH1A1 (0.46) | MEN1KMT2AHPGDHCAR3BRD4 | |
| SCHEMBL14800316 | 0.81 | MEN1 (0.54) | MEN1KMT2APTGER4SMN1; SMN2HTT | |
| SCHEMBL15774565 | 0.81 | HPGD (0.62) | MEN1KMT2APTGER4SMN1; SMN2HPGD | |
| SCHEMBL2937848 | 0.79 | HCAR3 (0.55) | MEN1KMT2APTGER4SMN1; SMN2HTT | |
| SCHEMBL2939210 | 0.78 | FGFR1 (0.54) | MEN1KMT2ASMN1; SMN2HTTHPGD | |
| SCHEMBL26672356 | 0.75 | MEN1 (0.56) | MEN1KMT2APTGER4SMN1; SMN2HTT | |
| SCHEMBL29556127 | 0.75 | MEN1 (0.56) | MEN1KMT2APTGER4SMN1; SMN2HTT | |
| SCHEMBL3437993 | 0.75 | KMT2A (0.58) | MEN1KMT2ASMN1; SMN2HTTTP53 | |
| SCHEMBL31147784 | 0.74 | TP53 (0.52) | MEN1KMT2ASMN1; SMN2HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123609-A1 | IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2011-10-06 | — | — | WO | disclosed |