Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31147882 | 0.88 | GAA (0.50) | GRIN2BALDH1A1KDM4EGAAHDAC6 | |
| SCHEMBL31147965 | 0.81 | HDAC6 (0.51) | GRIN2BGRIN1HDAC6 | |
| SCHEMBL2828598 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4ETSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL18913971 | 0.76 | GSK3A (0.46) | ALDH1A1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL15919718 | 0.75 | GSK3A (0.45) | ALDH1A1KDM4ETSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL13837758 | 0.75 | GSK3A (0.45) | ALDH1A1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL15701010 | 0.75 | GSK3A (0.45) | ALDH1A1KDM4ETSHRMAPK1SMN1; SMN2 | |
| SCHEMBL17020375 | 0.75 | TSHR (0.47) | ALDH1A1KDM4ETSHRMAPK1HSD17B10 | |
| SCHEMBL16138147 | 0.75 | F11 (0.47) | ALDH1A1KDM4ETSHRMAPK1HDAC6 | |
| SCHEMBL18602501 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4ETSHRMAPK1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695240-A2 | CYCLIC VINYL SULFONE WRN INHIBITORS | Nimbus Wadjet, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024215923-A2 | CYCLIC VINYL SULFONE WRN INHIBITORS | NIMBUS WADJET, INC. (US) | 2024-10-17 | — | — | WO | disclosed |