Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30628 | 0.88 | HSD17B2 (0.43) | HSD17B1HSD17B2 | |
| SCHEMBL31108 | 0.77 | HSD17B1 (0.50) | HSD17B1HSD17B2 | |
| SCHEMBL31446 | 0.76 | HSD17B1 (0.69) | HSD17B1HSD17B2 | |
| SCHEMBL31459 | 0.68 | HSD17B1 (0.77) | HSD17B1HSD17B2 | |
| SCHEMBL31477 | 0.68 | HSD17B1 (0.53) | HSD17B1HSD17B2 | |
| SCHEMBL24752 | 0.66 | HSD17B1 (1.00) | HSD17B1HSD17B2 | |
| SCHEMBL22550 | 0.66 | HSD17B1 (0.88) | HSD17B1HSD17B2 | |
| SCHEMBL24263 | 0.66 | HSD17B1 (1.00) | HSD17B1HSD17B2 | |
| SCHEMBL22633 | 0.63 | HSD17B1 (0.77) | HSD17B1HSD17B2 | |
| SCHEMBL31107 | 0.63 | HSD17B1 (0.53) | HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | disclosed |