Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21078251 | 0.73 | JAK1 (0.46) | ALDH1A1MAPTNPC1JAK1 | |
| SCHEMBL31148163 | 0.73 | USP2 (0.48) | SMN1; SMN2USP2ALOX15HSD17B10LMNA | |
| SCHEMBL19226472 | 0.72 | JAK1 (0.51) | ALDH1A1NPC1RAB9AJAK1 | |
| SCHEMBL21078209 | 0.72 | KDM4E (0.47) | ALDH1A1MAPTSMN1; SMN2NPC1JAK1 | |
| SCHEMBL31148136 | 0.71 | DRD3 (0.55) | ALDH1A1SMN1; SMN2USP2ALOX15HSD17B10 | |
| SCHEMBL31148132 | 0.71 | DRD3 (0.55) | ALDH1A1SMN1; SMN2USP2ALOX15HSD17B10 | |
| SCHEMBL17888457 | 0.70 | JAK1 (0.48) | ALDH1A1NPC1JAK1 | |
| SCHEMBL31148242 | 0.70 | HRH3 (0.51) | ALDH1A1MAPTSMN1; SMN2USP2ALOX15 | |
| SCHEMBL3142743 | 0.70 | NLRP3 (0.38) | MAPTSMN1; SMN2RAB9AJAK1HSD11B1 | |
| SCHEMBL31148256 | 0.70 | HSD11B1 (0.41) | ALDH1A1SMN1; SMN2USP2ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695236-A1 | SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024216094-A1 | SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-10-17 | — | — | WO | disclosed |