Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25253501 | 1.00 | NR3C1 (0.40) | NR3C1SCN8ASCN10AHIF1AEPAS1 | |
| SCHEMBL24150182 | 0.92 | DGAT2 (0.39) | NR3C1SMN1; SMN2 | |
| SCHEMBL31148861 | 0.92 | DGAT2 (0.39) | NR3C1SMN1; SMN2 | |
| SCHEMBL24150143 | 0.85 | NR3C1 (0.41) | NR3C1SMN1; SMN2 | |
| SCHEMBL26225429 | 0.82 | JAK2 (0.34) | — | |
| SCHEMBL31162534 | 0.82 | JAK2 (0.34) | — | |
| SCHEMBL25296799 | 0.82 | DGAT2 (0.38) | NR3C1SMN1; SMN2 | |
| SCHEMBL30219010 | 0.82 | DGAT2 (0.38) | NR3C1SMN1; SMN2 | |
| SCHEMBL30468916 | 0.82 | DGAT2 (0.38) | NR3C1SMN1; SMN2 | |
| SCHEMBL26073868 | 0.82 | DGAT2 (0.38) | NR3C1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118475561-A | Aryltetrahydropyridazine derivatives or salts thereof, pesticides containing the same and methods of use thereof | 日本农药株式会社 | 2024-08-09 | — | — | CN | disclosed |