Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31149359 | 0.75 | NOTUM (0.31) | — | |
| SCHEMBL16178941 | 0.72 | AKR1B1 (0.45) | ALDH1A1KMT2AMAPK1MEN1L3MBTL1 | |
| SCHEMBL22669220 | 0.70 | ALDH1A1 (0.42) | ALDH1A1IDO1KMT2AMAPK1MEN1 | |
| SCHEMBL31149390 | 0.70 | ALDH1A1 (0.41) | ALDH1A1IDO1KMT2AMAPK1MEN1 | |
| SCHEMBL449605 | 0.69 | ALDH1A1 (0.42) | ALDH1A1KMT2AMAPK1MEN1L3MBTL1 | |
| SCHEMBL31378778 | 0.67 | ALDH1A1 (0.38) | ALDH1A1IDO1KMT2AMAPK1MEN1 | |
| SCHEMBL31378826 | 0.67 | ALDH1A1 (0.38) | ALDH1A1IDO1KMT2AMAPK1MEN1 | |
| SCHEMBL31378926 | 0.67 | ALDH1A1 (0.38) | ALDH1A1IDO1KMT2AMAPK1MEN1 | |
| SCHEMBL3381895 | 0.65 | PGR (0.41) | ALDH1A1IDO1KMT2AMAPK1MEN1 | |
| SCHEMBL6770407 | 0.65 | ALDH1A1 (0.38) | ALDH1A1IDO1KMT2AMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480049-A | PKMYT1 inhibitor and preparation method and application thereof | 南京同诺康医药科技有限公司 | 2024-08-13 | — | — | CN | disclosed |