Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312875 | 0.87 | KDM4E (0.58) | MAOBCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL312402 | 0.85 | HPGD (0.43) | MAOBHPGDKDM4EHSD17B10CYP2C9 | |
| SCHEMBL311971 | 0.83 | AKR1B1 (0.51) | MAOBCYP3A4MEN1KMT2AMAPK1 | |
| SCHEMBL311598 | 0.83 | CSNK2A2 (0.46) | MAOBCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL313004 | 0.83 | ATM (0.52) | ARMAOBATMCYP3A4MAPT | |
| SCHEMBL313348 | 0.82 | ATM (0.49) | ARMAOBATMCYP3A4MAPT | |
| SCHEMBL311987 | 0.75 | ATM (0.50) | ARMAOBATMCYP3A4MAPT | |
| SCHEMBL312748 | 0.74 | TYR (0.44) | MAOBMAPK1HPGDABL1KDM4E | |
| SCHEMBL312259 | 0.73 | MAOB (0.40) | MAOBHPGDABL1KDM4EHSD17B10 | |
| SCHEMBL311138 | 0.73 | HPGD (0.58) | MAOBCYP3A4MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |