Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 6/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312009 | 0.87 | KDM4E (0.58) | MAOBMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL311723 | 0.85 | HPGD (0.43) | MAOBMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL313004 | 0.85 | ATM (0.52) | ATMARMAOBMEN1KMT2A | |
| SCHEMBL313038 | 0.82 | HPGD (0.46) | MAOBMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL311513 | 0.82 | AR (0.45) | ATMARMAOBMEN1KMT2A | |
| SCHEMBL312841 | 0.82 | AKR1B1 (0.50) | MAOBMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL311987 | 0.81 | ATM (0.50) | ATMARMAOBMEN1KMT2A | |
| SCHEMBL311620 | 0.77 | AKR1B1 (0.43) | MAOBMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL312748 | 0.77 | TYR (0.44) | MAOBEGFRRETKDRABL1 | |
| SCHEMBL312670 | 0.77 | HPGD (0.42) | MAOBMEN1KMT2ACYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |