Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | QPCT | Q16769 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 3/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311598 | 0.92 | CSNK2A2 (0.46) | AKR1B1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL312875 | 0.90 | KDM4E (0.58) | HPGDKDM4EHSD17B10LMNAALDH1A1 | |
| SCHEMBL312223 | 0.84 | AKR1B1 (0.56) | AKR1B1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL312841 | 0.83 | AKR1B1 (0.50) | AKR1B1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL311513 | 0.83 | AR (0.45) | HPGDKDM4EHSD17B10LMNAALDH1A1 | |
| SCHEMBL312402 | 0.82 | HPGD (0.43) | HPGDKDM4EHSD17B10LMNAALDH1A1 | |
| SCHEMBL312259 | 0.80 | MAOB (0.40) | AKR1B1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL311620 | 0.79 | AKR1B1 (0.43) | AKR1B1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL311904 | 0.78 | HPGD (0.40) | AKR1B1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL311364 | 0.77 | HPGD (0.44) | AKR1B1HPGDKDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |