Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2124400 | 0.82 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL2122874 | 0.79 | HCRTR1 (0.35) | — | |
| SCHEMBL311401 | 0.78 | PDE8B (0.32) | — | |
| SCHEMBL2122677 | 0.78 | CYP11B1 (0.36) | AKT1AKT2 | |
| SCHEMBL2124331 | 0.74 | ALDH1A1 (0.40) | — | |
| SCHEMBL2512523 | 0.73 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL2120890 | 0.72 | HCRTR1 (0.33) | AKT1AKT2 | |
| SCHEMBL2517435 | 0.72 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL2123540 | 0.71 | KMT2A (0.34) | — | |
| SCHEMBL2124844 | 0.69 | AKT1 (0.32) | AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093255-B2 | Imidazo[1,2-A]pyrimidines as orexin receptor antagonists | GLAXO GROUP LIMITED (GB) | 2012-01-10 | — | — | US | disclosed |