Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | BRD2 | P25440 | 2/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819366 | 0.91 | KMT2A (0.54) | ALDH1A1KMT2AGAALMNAUSP2 | |
| Hydrochloric Acid SCHEMBL3008966 | 0.89 | KMT2A (0.53) | ALDH1A1KMT2AGAALMNAUSP2 | |
| SCHEMBL2823333 | 0.89 | ALDH1A1 (0.59) | ALDH1A1KMT2AGAALMNAMCOLN3 | |
| SCHEMBL2820535 | 0.86 | KMT2A (0.64) | ALDH1A1KMT2AGAAMCOLN3USP2 | |
| Hydrochloric Acid SCHEMBL3122697 | 0.85 | KMT2A (0.62) | ALDH1A1KMT2AGAAMCOLN3USP2 | |
| SCHEMBL2821865 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KMT2AGAALMNAMCOLN3 | |
| SCHEMBL2818870 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KMT2AGAAMCOLN3USP2 | |
| SCHEMBL2823053 | 0.82 | L3MBTL1 (0.48) | ALDH1A1KMT2ALMNAMCOLN3HTT | |
| Hydrochloric Acid SCHEMBL2823218 | 0.81 | L3MBTL1 (0.47) | ALDH1A1KMT2ALMNAMCOLN3HTT | |
| SCHEMBL2821664 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KMT2AGAAUSP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700586-B2 | Arylsulfonamide derivatives for use as ccr3 antagonists in the treatment of inflammatory and immunological disorders | AXIKIN PHARMACEUTICALS, INC. (US) | 2010-04-20 | — | — | US | claimed |