SCHEMBL31153418

SCHEMBL31153418

CCC(=O)N1CCc2c(c(N(C)c3ccc(Cl)nc3)nn2C2CCOCC2)C1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CREBBP Q92793 20/20 0.47
▸ BRD4 O60885 9/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34471816 0.75 CREBBP (0.53) CREBBPBRD4
SCHEMBL34470772 0.74 CREBBP (0.42) CREBBPBRD4
SCHEMBL34471092 0.73 CREBBP (0.42) CREBBPBRD4
SCHEMBL31208162 0.72 CREBBP (0.49) CREBBPBRD4
SCHEMBL31208166 0.72 CREBBP (0.49) CREBBPBRD4
SCHEMBL31153425 0.71 PDE4D (0.35) CREBBP
SCHEMBL31153556 0.71 BRD4 (0.62) CREBBPBRD4
SCHEMBL31153419 0.69 CREBBP (0.42) CREBBPBRD4
SCHEMBL31153407 0.69 TUBB4A (0.38) CREBBP
SCHEMBL34471831 0.69 CREBBP (0.49) CREBBPBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090317-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2026-04-30 — — WO disclosed
EP-4698544-A1 COMPOUNDS AND USES THEREOF Foghorn Therapeutics Inc. (US) 2026-02-25 — — EP disclosed
WO-2024220946-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2024-10-24 — — WO disclosed
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