Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 9/20 | 0.42 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | BRD1 | O95696 | 1/20 | 0.37 |
| ▸ | TAF1 | P21675 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.37 |
| ▸ | BRWD1 | Q9NSI6 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31153425 | 0.90 | PDE4D (0.35) | CREBBPPDE4DNR3C1SPR | |
| SCHEMBL31153407 | 0.90 | TUBB4A (0.38) | CREBBPPDE4DNR3C1SPRIRAK4 | |
| SCHEMBL31153553 | 0.79 | CFTR (0.35) | CREBBPBRD4NR3C1 | |
| SCHEMBL31153458 | 0.79 | TUBB4A (0.38) | CREBBPBRD4PDE4DNR3C1IRAK4 | |
| SCHEMBL19657665 | 0.76 | CREBBP (0.48) | CREBBPBRD4TRIM24BRD1TAF1 | |
| SCHEMBL22822778 | 0.74 | CREBBP (0.48) | CREBBPBRD4TRIM24BRD1TAF1 | |
| SCHEMBL31153490 | 0.73 | NR3C1 (0.34) | CREBBPPDE4DNR3C1IRAK4 | |
| SCHEMBL31153418 | 0.69 | CREBBP (0.47) | CREBBPBRD4 | |
| SCHEMBL29704418 | 0.63 | PTGER4 (0.40) | CREBBPBRD4IRAK4 | |
| SCHEMBL19657727 | 0.63 | PTGER4 (0.40) | CREBBPBRD4IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698544-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220946-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2024-10-24 | — | — | WO | disclosed |