Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312401 | 0.86 | KDM4E (0.59) | HPGDKDM4EHSD17B10LMNACYP3A4 | |
| SCHEMBL311987 | 0.85 | ATM (0.50) | HPGDKDM4EHSD17B10LMNACYP3A4 | |
| SCHEMBL311431 | 0.82 | HPGD (0.46) | HPGDKDM4EHSD17B10LMNACYP3A4 | |
| SCHEMBL311723 | 0.82 | HPGD (0.43) | HPGDKDM4EHSD17B10LMNACYP3A4 | |
| SCHEMBL312214 | 0.81 | HPGD (0.47) | HPGDKDM4EHSD17B10LMNACYP3A4 | |
| SCHEMBL311355 | 0.81 | AKR1B1 (0.51) | HPGDKDM4EHSD17B10LMNACYP3A4 | |
| SCHEMBL312402 | 0.76 | HPGD (0.43) | HPGDKDM4EHSD17B10LMNACYP2C19 | |
| SCHEMBL312366 | 0.73 | KDM4E (0.58) | HPGDKDM4EHSD17B10LMNACYP3A4 | |
| SCHEMBL311828 | 0.73 | CYP2D6 (0.46) | HPGDKDM4EHSD17B10LMNACYP3A4 | |
| SCHEMBL311794 | 0.73 | CYP3A4 (0.44) | HPGDKDM4EHSD17B10CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |