Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TNKS | O95271 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311355 | 0.89 | AKR1B1 (0.51) | KDM4EHPGDHSD17B10LMNATNKS | |
| SCHEMBL312214 | 0.89 | HPGD (0.47) | KDM4EHPGDHSD17B10LMNAMEN1 | |
| SCHEMBL311987 | 0.87 | ATM (0.50) | KDM4EHPGDHSD17B10LMNAMEN1 | |
| SCHEMBL311535 | 0.86 | HPGD (0.44) | KDM4EHPGDHSD17B10LMNATNKS | |
| SCHEMBL312366 | 0.85 | KDM4E (0.58) | KDM4EHPGDHSD17B10LMNATNKS | |
| SCHEMBL324201 | 0.81 | HPGD (0.61) | KDM4EHPGDHSD17B10LMNATNKS | |
| SCHEMBL312009 | 0.81 | KDM4E (0.58) | KDM4EHPGDHSD17B10LMNATNKS | |
| SCHEMBL311129 | 0.80 | HPGD (0.63) | KDM4EHPGDHSD17B10LMNATNKS | |
| SCHEMBL311720 | 0.80 | HPGD (0.59) | KDM4EHPGDHSD17B10LMNATNKS | |
| SCHEMBL312126 | 0.79 | MAOB (0.50) | KDM4EHPGDHSD17B10LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |