Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 4/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29704418 | 0.86 | PTGER4 (0.40) | CFTRKDM4CCREBBPMAPK1SSTR4 | |
| SCHEMBL19657727 | 0.86 | PTGER4 (0.40) | CFTRKDM4CCREBBPMAPK1SSTR4 | |
| SCHEMBL31153553 | 0.75 | CFTR (0.35) | CFTRKDM4CCREBBPKCNJ6KCNJ5 | |
| SCHEMBL31153425 | 0.72 | PDE4D (0.35) | CFTRKDM4CCREBBPMAPK1 | |
| SCHEMBL19657665 | 0.72 | CREBBP (0.48) | CFTRCREBBP | |
| SCHEMBL31153569 | 0.72 | CREBBP (0.62) | CREBBP | |
| SCHEMBL23530030 | 0.72 | CFTR (0.37) | CFTRKDM4CPIK3CA | |
| SCHEMBL25078198 | 0.72 | CFTR (0.44) | CFTRKDM4CHSD11B1CREBBPPIK3CA | |
| SCHEMBL22822778 | 0.70 | CREBBP (0.48) | CREBBPSSTR4 | |
| SCHEMBL28732090 | 0.68 | KDM4C (0.41) | KDM4CMAPK1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698544-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220946-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2024-10-24 | — | — | WO | disclosed |