Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 5/20 | 0.48 |
| ▸ | CFTR | P13569 | 2/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 7/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | BRD1 | O95696 | 1/20 | 0.37 |
| ▸ | TAF1 | P21675 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.37 |
| ▸ | BRWD1 | Q9NSI6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22822778 | 0.85 | CREBBP (0.48) | CREBBPFPR1BRD4TRIM24BRD1 | |
| SCHEMBL26098592 | 0.80 | PTGER4 (0.39) | CREBBPCFTRSPRPDE7AP2RX7 | |
| SCHEMBL19657320 | 0.77 | CREBBP (0.52) | CREBBPSPRPDE7A | |
| SCHEMBL31153419 | 0.76 | CREBBP (0.42) | CREBBPSPRBRD4TRIM24BRD1 | |
| SCHEMBL23530030 | 0.74 | CFTR (0.37) | CFTR | |
| SCHEMBL29549913 | 0.74 | PTGER4 (0.42) | PDE7A | |
| SCHEMBL23529922 | 0.74 | PTGER4 (0.42) | PDE7A | |
| SCHEMBL29704418 | 0.74 | PTGER4 (0.40) | CREBBPCFTRBRD4 | |
| SCHEMBL19657727 | 0.74 | PTGER4 (0.40) | CREBBPCFTRBRD4 | |
| SCHEMBL31153524 | 0.72 | CFTR (0.39) | CREBBPCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205536-A2 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | WO | disclosed |