SCHEMBL31153553

SCHEMBL31153553

CN(c1ccc(Cl)cc1)c1nn(C2CCOCC2)c2ccc(C(=O)O)nc12

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CFTR P13569 3/20 0.35
▸ KDM4C Q9H3R0 2/20 0.35
▸ LTC4S Q16873 4/20 0.35
▸ NR3C1 P04150 1/20 0.35
▸ CREBBP Q92793 3/20 0.34
▸ BRD4 O60885 2/20 0.34
▸ PDE1A P54750 1/20 0.34
▸ PDE1B Q01064 1/20 0.34
▸ PDE1C Q14123 1/20 0.34
▸ RXRA P19793 1/20 0.34
▸ NR4A2 P43354 1/20 0.34
▸ KCNJ6 P48051 1/20 0.33
▸ KCNJ5 P48544 1/20 0.33
▸ KCNJ3 P48549 1/20 0.33
▸ CNR1 P21554 1/20 0.33
▸ PDE9A O76083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31153458 0.90 TUBB4A (0.38) KDM4CNR3C1CREBBPBRD4PDE1A
SCHEMBL31153425 0.89 PDE4D (0.35) CFTRKDM4CLTC4SNR3C1CREBBP
SCHEMBL31153419 0.79 CREBBP (0.42) NR3C1CREBBPBRD4
SCHEMBL31153407 0.79 TUBB4A (0.38) NR3C1CREBBPKCNJ6KCNJ5KCNJ3
SCHEMBL31153490 0.76 NR3C1 (0.34) KDM4CNR3C1CREBBPPDE1APDE1B
SCHEMBL31153524 0.75 CFTR (0.39) CFTRKDM4CCREBBPKCNJ6KCNJ5
SCHEMBL19657665 0.66 CREBBP (0.48) CFTRCREBBPBRD4
SCHEMBL23530030 0.66 CFTR (0.37) CFTRKDM4CPDE1APDE1BPDE1C
SCHEMBL29704418 0.65 PTGER4 (0.40) CFTRKDM4CCREBBPBRD4KCNJ6
SCHEMBL19657727 0.65 PTGER4 (0.40) CFTRKDM4CCREBBPBRD4KCNJ6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698544-A1 COMPOUNDS AND USES THEREOF Foghorn Therapeutics Inc. (US) 2026-02-25 — — EP disclosed
WO-2024220946-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2024-10-24 — — WO disclosed
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