Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 11/20 | 0.78 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.78 |
| ▸ | SCN1A | P35498 | 5/20 | 0.78 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.78 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.78 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.78 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.78 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122855 | 0.90 | SCN3A (0.75) | SCN3ASCN9ASCN1ASCN8ASCN5A | |
| SCHEMBL3163478 | 0.89 | SCN3A (0.69) | SCN3ASCN9ASCN1ASCN8ASCN5A | |
| SCHEMBL3119441 | 0.88 | SCN3A (1.00) | SCN3ASCN9ASCN1ASCN8ASCN5A | |
| SCHEMBL3122286 | 0.87 | SCN3A (0.60) | SCN3ASCN9ASCN1ASCN8ASCN5A | |
| SCHEMBL3164067 | 0.87 | SCN3A (0.66) | SCN3ASCN9ASCN1ASCN8ASCN5A | |
| SCHEMBL3162787 | 0.85 | SCN3A (0.63) | SCN3ASCN9ASCN1ASCN8ASCN5A | |
| SCHEMBL3123451 | 0.85 | SCN3A (0.60) | SCN3ASCN9ASCN1ASCN8ASCN5A | |
| SCHEMBL3169276 | 0.83 | SCN3A (0.61) | SCN3ASCN9ASCN1ASCN8ASCN5A | |
| SCHEMBL3169845 | 0.83 | SCN3A (0.61) | SCN3ASCN9ASCN1ASCN8ASCN5A | |
| SCHEMBL3167423 | 0.82 | SCN3A (0.63) | SCN3ASCN9ASCN1ASCN8ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035166-A1 | BENZAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010035166-A1 | BENZAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |