Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 12/20 | 0.60 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.57 |
| ▸ | SCN1A | P35498 | 3/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.57 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.57 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.57 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122855 | 0.89 | SCN3A (0.75) | SCN3ASCN9ASCN1ASCN2ASCN10A | |
| SCHEMBL3173419 | 0.88 | SCN3A (0.57) | SCN3ASCN9ASCN1ASCN2ASCN10A | |
| SCHEMBL3131221 | 0.88 | SCN3A (0.58) | SCN3ASCN9ASCN1ASCN2ASCN10A | |
| SCHEMBL3129670 | 0.87 | SCN3A (0.79) | SCN3ASCN9ASCN1ASCN2ASCN10A | |
| SCHEMBL3158696 | 0.86 | SCN3A (0.57) | SCN3ASCN9ASCN1ASCN2ASCN10A | |
| SCHEMBL3115353 | 0.85 | SCN3A (0.78) | SCN3ASCN9ASCN1ASCN2ASCN10A | |
| SCHEMBL3159811 | 0.84 | SCN3A (0.58) | SCN3ASCN9ASCN1ASCN2ASCN10A | |
| SCHEMBL13452429 | 0.83 | SCN3A (0.53) | SCN3ASCN9ASCN1ASCN2ASCN10A | |
| SCHEMBL3162511 | 0.83 | SCN3A (0.56) | SCN3ASCN9ASCN1ASCN2ASCN10A | |
| SCHEMBL3158722 | 0.81 | SCN3A (0.63) | SCN3ASCN9ASCN1ASCN2ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035166-A1 | BENZAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010035166-A1 | BENZAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |