Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 14/20 | 0.75 |
| ▸ | SCN1A | P35498 | 3/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.64 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.64 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.64 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.64 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3115353 | 0.90 | SCN3A (0.78) | SCN3ASCN1ASCN9ASCN2ASCN10A | |
| SCHEMBL3123451 | 0.89 | SCN3A (0.60) | SCN3ASCN1ASCN9ASCN2ASCN10A | |
| SCHEMBL3127375 | 0.87 | SCN3A (0.73) | SCN3ASCN1ASCN9ASCN2ASCN10A | |
| SCHEMBL4458928 | 0.86 | SCN3A (0.70) | SCN3ASCN1ASCN9ASCN2ASCN10A | |
| SCHEMBL3125226 | 0.85 | SCN3A (1.00) | SCN3ASCN1ASCN9ASCN2ASCN10A | |
| SCHEMBL3168903 | 0.85 | SCN3A (0.70) | SCN3ASCN1ASCN9ASCN2ASCN10A | |
| SCHEMBL3060620 | 0.82 | SCN9A (0.54) | SCN3ASCN1ASCN9ASCN2ASCN10A | |
| SCHEMBL3154148 | 0.80 | SCN3A (0.71) | SCN3ASCN1ASCN9ASCN2ASCN10A | |
| SCHEMBL3159810 | 0.79 | SCN3A (0.75) | SCN3ASCN1ASCN9ASCN2ASCN10A | |
| SCHEMBL3154263 | 0.79 | SCN3A (0.86) | SCN3ASCN1ASCN9ASCN2ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035166-A1 | BENZAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2010-04-01 | — | — | WO | claimed |
| WO-2010035166-A1 | BENZAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010035166-A1 | BENZAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |