Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | S100A4 | P26447 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.48 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16870940 | 1.00 | TTR (0.54) | TTRS100A4MEN1KMT2ACDC25B | |
| SCHEMBL6905214 | 0.92 | TTR (0.64) | TTRS100A4MEN1KMT2ACDC25B | |
| SCHEMBL5681748 | 0.84 | CES1 (0.52) | TTRS100A4MEN1KMT2ADNMT1 | |
| SCHEMBL8987675 | 0.83 | HSP90AA1 (0.67) | TTRS100A4DNMT1HSP90AA1PTPRC | |
| SCHEMBL1712245 | 0.82 | ELANE (0.55) | TTRMEN1KMT2ACDC25BDNMT1 | |
| SCHEMBL1712777 | 0.82 | TTR (0.50) | TTRS100A4MEN1KMT2ACDC25B | |
| SCHEMBL16107097 | 0.82 | BCL2 (0.62) | TTRMEN1KMT2ACDC25BDNMT1 | |
| SCHEMBL29164293 | 0.82 | TTR (0.50) | TTRS100A4MEN1KMT2ACDC25B | |
| SCHEMBL22233096 | 0.80 | S100A4 (0.50) | TTRS100A4MEN1KMT2ACDC25B | |
| SCHEMBL1712771 | 0.80 | TTR (0.51) | TTRS100A4MEN1KMT2ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812412-A | Preparation method of spirotrienone and coumarin and derivatives thereof | 黄淮学院 | 2024-10-22 | — | — | CN | disclosed |