SCHEMBL8987675

SCHEMBL8987675

O=C1c2cc(Cl)ccc2-c2c(Cl)cc(Cl)cc21

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.67
S100A4 P26447 2/20 0.61
ITGA1 P56199 1/20 0.45
PPOX P50336 1/20 0.45
CES1 P23141 4/20 0.41
TGM2 P21980 1/20 0.41
DNMT1 P26358 1/20 0.41
USP8 P40818 2/20 0.41
USP7 Q93009 2/20 0.41
USP47 Q96K76 1/20 0.41
TP53 P04637 1/20 0.41
AHR P35869 1/20 0.41
PTPRC P08575 1/20 0.40
METAP1 P53582 1/20 0.39
PTPN1 P18031 1/20 0.39
TTR P02766 1/20 0.39
PTPN11 Q06124 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5681748 0.84 CES1 (0.52) HSP90AA1S100A4CES1TGM2DNMT1
SCHEMBL16870940 0.83 TTR (0.54) HSP90AA1S100A4ITGA1CES1DNMT1
SCHEMBL31154504 0.83 TTR (0.54) HSP90AA1S100A4ITGA1CES1DNMT1
SCHEMBL4229683 0.82 S100A4 (0.80) HSP90AA1S100A4ITGA1PPOXCES1
SCHEMBL30345128 0.82 S100A4 (0.90) HSP90AA1S100A4ITGA1PPOXCES1
SCHEMBL353693 0.82 S100A4 (0.80) HSP90AA1S100A4ITGA1PPOXCES1
SCHEMBL1133148 0.82 S100A4 (0.90) HSP90AA1S100A4ITGA1PPOXCES1
SCHEMBL4319897 0.77 S100A4 (0.71) HSP90AA1S100A4ITGA1PPOXCES1
SCHEMBL29581505 0.77 S100A4 (0.71) HSP90AA1S100A4ITGA1PPOXCES1
SCHEMBL11601993 0.77 CES1 (0.50) HSP90AA1S100A4CES1TGM2DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400972-B1 Fluorescent degree of cure monitors MINNESOTA MINING & MFG (US) 1996-07-03 EP disclosed
US-5182316-A Forming a UV-detectable fluorophore in a mixture of hydride containing silicone, unsaturated silicone, cationically sensitive compound and a latent dibenzofulvene MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-01-26 US disclosed
US-5118559-A Dibenzofulvene compound MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-06-02 US disclosed
US-5047444-A Hydrosilatable polysiloxanes, unsaturated compounds and a dibenzofulvene chromogen; coatings MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-10 US disclosed
EP-0400972-A2 Fluorescent degree of cure monitors MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-12-05 EP disclosed
US-4888255-A PREVENTION OF VOLTAGE DROP IN LITHIUM BATTERY HITACHI MAXELL, LTD. (JP) 1989-12-19 US disclosed
EP-0296589-A2 Non-aqueous electrochemical cell Hitachi Maxell Ltd. (JP) 1988-12-28 EP disclosed