Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3115498 | 1.00 | NR4A2 (0.53) | NR4A2NR4A1NR4A3LMNASPHK2 | |
| SCHEMBL3110948 | 0.93 | NR4A2 (0.54) | NR4A2NR4A1NR4A3LMNASPHK2 | |
| SCHEMBL3110954 | 0.93 | NR4A2 (0.54) | NR4A2NR4A1NR4A3LMNASPHK2 | |
| SCHEMBL3110254 | 0.90 | PPARD (0.51) | SPHK2SPHK1FFAR1PPARDPPARA | |
| SCHEMBL3105038 | 0.90 | NR4A2 (0.48) | NR4A2NR4A1NR4A3LMNASPHK2 | |
| SCHEMBL3110246 | 0.90 | PPARD (0.51) | SPHK2SPHK1FFAR1PPARDPPARA | |
| SCHEMBL3105034 | 0.90 | NR4A2 (0.48) | NR4A2NR4A1NR4A3LMNASPHK2 | |
| SCHEMBL3115372 | 0.90 | NR4A2 (0.54) | NR4A2NR4A1NR4A3LMNASPHK2 | |
| SCHEMBL3115382 | 0.90 | NR4A2 (0.54) | NR4A2NR4A1NR4A3LMNASPHK2 | |
| SCHEMBL3115554 | 0.89 | FFAR1 (0.51) | SPHK2SPHK1FFAR1RAB9APPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312308-A1 | SUBSTITUTED ACETIC ACID DERIVATIVES | WYETH (US) | 2008-12-18 | — | — | US | claimed |
| US-7803835-B2 | Substituted acetic acid derivatives | WYETH LLC (US) | 2010-09-28 | — | — | US | disclosed |
| US-20080312308-A1 | SUBSTITUTED ACETIC ACID DERIVATIVES | WYETH (US) | 2008-12-18 | — | — | US | disclosed |
| US-7411083-B2 | Substituted acetic acid derivatives | WYETH (US) | 2008-08-12 | — | — | US | disclosed |
| US-20060247298-A1 | Substituted acetic acid derivatives | WYETH (US) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312308-A1 | SUBSTITUTED ACETIC ACID DERIVATIVES | AADAC, ACACA, AANAT | NR4A2 2770/4885NR4A1 3836/4885NR4A3 2430/4885 |
| US-20060247298-A1 | Substituted acetic acid derivatives | AADAC, ACACA, AANAT | NR4A2 2770/4885NR4A1 3836/4885NR4A3 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.