Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 14/20 | 0.42 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.38 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31155958 | 0.89 | USP1 (0.48) | USP1WDR48STIM1ORAI1 | |
| SCHEMBL31255082 | 0.86 | USP1 (0.46) | USP1WDR48STIM1ORAI1GRIN1 | |
| SCHEMBL30462100 | 0.83 | STIM1 (0.42) | USP1WDR48STIM1ORAI1 | |
| SCHEMBL29043925 | 0.83 | STIM1 (0.42) | USP1WDR48STIM1ORAI1 | |
| SCHEMBL31155886 | 0.81 | USP1 (0.48) | USP1WDR48 | |
| SCHEMBL31155897 | 0.79 | STIM1 (0.42) | USP1WDR48STIM1ORAI1 | |
| SCHEMBL31155911 | 0.78 | USP1 (0.43) | USP1 | |
| SCHEMBL31537663 | 0.77 | USP1 (0.43) | USP1WDR48 | |
| SCHEMBL31254943 | 0.77 | USP1 (0.44) | USP1WDR48 | |
| SCHEMBL31254686 | 0.77 | USP1 (0.50) | USP1WDR48STIM1ORAI1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208292-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITOR, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2024-10-10 | — | — | WO | disclosed |