Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 2/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.42 |
| ▸ | USP1 | O94782 | 9/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31155958 | 0.89 | USP1 (0.48) | STIM1ORAI1USP1PTGS2PTGS1 | |
| SCHEMBL31155886 | 0.80 | USP1 (0.48) | USP1PTGS2PTGS1WDR48CYP1A2 | |
| SCHEMBL31155860 | 0.79 | USP1 (0.42) | STIM1ORAI1USP1WDR48 | |
| SCHEMBL31255082 | 0.78 | USP1 (0.46) | STIM1ORAI1USP1PTGS2PTGS1 | |
| SCHEMBL31155904 | 0.77 | CCR1 (0.38) | STIM1ORAI1USP1PTGS2PTGS1 | |
| SCHEMBL31155941 | 0.77 | USP1 (0.44) | USP1PTGS2PTGS1 | |
| SCHEMBL25184834 | 0.76 | STIM1 (0.48) | STIM1ORAI1USP1WDR48MAPT | |
| SCHEMBL30462000 | 0.76 | USP1 (0.45) | STIM1ORAI1USP1PTGS2PTGS1 | |
| SCHEMBL30414386 | 0.76 | STIM1 (0.48) | STIM1ORAI1USP1WDR48MAPT | |
| SCHEMBL29043912 | 0.76 | USP1 (0.45) | STIM1ORAI1USP1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208292-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITOR, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2024-10-10 | — | — | WO | disclosed |