Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 20/20 | 0.49 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31155889 | 0.96 | USP1 (0.46) | USP1 | |
| SCHEMBL31254588 | 0.87 | HDAC1 (0.40) | USP1WDR48 | |
| SCHEMBL31155920 | 0.85 | USP1 (0.51) | USP1WDR48 | |
| SCHEMBL31254619 | 0.85 | USP1 (0.37) | USP1WDR48 | |
| SCHEMBL31155944 | 0.85 | USP1 (0.50) | USP1WDR48 | |
| SCHEMBL31155888 | 0.84 | USP1 (0.42) | USP1WDR48 | |
| SCHEMBL31155879 | 0.83 | USP1 (0.51) | USP1WDR48 | |
| SCHEMBL31255009 | 0.83 | USP1 (0.45) | USP1WDR48 | |
| SCHEMBL31155956 | 0.83 | USP1 (0.43) | USP1WDR48 | |
| SCHEMBL31254974 | 0.81 | USP1 (0.43) | USP1WDR48 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233665-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| WO-2024208292-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITOR, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2024-10-10 | — | — | WO | disclosed |