SCHEMBL31155889

SCHEMBL31155889

COc1cnc(Cl)nc1OCc1ccc(-c2nc(C(F)(F)F)cn2C2CCC2)cc1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31155874 0.96 USP1 (0.49) USP1
SCHEMBL31155920 0.84 USP1 (0.51) USP1
SCHEMBL31254588 0.83 HDAC1 (0.40) USP1
SCHEMBL31155944 0.83 USP1 (0.50) USP1
SCHEMBL31255009 0.81 USP1 (0.45) USP1
SCHEMBL31155879 0.81 USP1 (0.51) USP1
SCHEMBL31155956 0.81 USP1 (0.43) USP1
SCHEMBL31254619 0.81 USP1 (0.37) USP1
SCHEMBL31155888 0.80 USP1 (0.42) USP1
SCHEMBL31254997 0.80 USP1 (0.48) USP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024208292-A1 UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITOR, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF 江苏亚虹医药科技股份有限公司 2024-10-10 — — WO disclosed
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