Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.57 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16339983 | 1.00 | HRH4 (0.57) | HRH4RHEBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL27518065 | 0.86 | KDM4E (0.57) | HRH4RHEBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL922207 | 0.82 | HRH4 (0.55) | HRH4RHEBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8210176 | 0.82 | RHEB (0.43) | HRH4RHEBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL30295665 | 0.81 | FLT3 (0.57) | HRH4RHEBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL924331 | 0.81 | FLT3 (0.57) | HRH4RHEBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL20505087 | 0.81 | FLT3 (0.57) | HRH4RHEBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL15511675 | 0.81 | FLT3 (0.57) | HRH4RHEBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8655451 | 0.80 | HRH4 (0.56) | HRH4KDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL20761800 | 0.79 | FLT3 (0.63) | HRH4FLT3PDGFRBKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676912-A2 | COMPOUNDS, COMPOSITIONS, AND METHOD OF INHIBITING TAU PROTEIN AND ALPHA-SYNUCLEIN AGGREGATION | Purdue Research Foundation (US) | 2026-01-14 | — | — | EP | disclosed |
| US-20250241890-A1 | 1,4-DIUREAS AND 1,4-DITHIOUREAS AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2025-07-31 | — | — | US | disclosed |
| WO-2024206127-A2 | COMPOUNDS, COMPOSITIONS, AND METHOD OF INHIBITING TAU PROTEIN AND ALPHA-SYNUCLEIN AGGREGATION | PURDUE RESEARCH FOUNDATION (US) | 2024-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250241890-A1 | 1,4-DIUREAS AND 1,4-DITHIOUREAS AND USES THEREOF | SNCA, PARK7, SYNCRIP | HRH4 4019/4885RHEB 1139/4885KDM4E 4288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.