Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31156465 | 0.87 | NPSR1 (0.56) | NPSR1ALDH1A1TSHRKDM4EL3MBTL1 | |
| SCHEMBL8382994 | 0.82 | NPSR1 (0.59) | NPSR1ALDH1A1TSHRKDM4EL3MBTL1 | |
| SCHEMBL8384543 | 0.78 | NPSR1 (0.53) | NPSR1ALDH1A1TSHRKDM4EL3MBTL1 | |
| SCHEMBL22208277 | 0.78 | ADORA1 (0.66) | NPSR1ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL4787080 | 0.72 | LMNA (0.50) | NPSR1ALDH1A1TSHRKDM4EL3MBTL1 | |
| SCHEMBL4748855 | 0.72 | NPSR1 (0.54) | NPSR1ALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL4787255 | 0.72 | KDM4E (0.70) | NPSR1ALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL14070104 | 0.71 | NPSR1 (0.45) | NPSR1ALDH1A1TSHRKDM4EL3MBTL1 | |
| SCHEMBL8379758 | 0.71 | KMT2A (0.43) | NPSR1ALDH1A1TSHRKDM4EL3MBTL1 | |
| SCHEMBL4745137 | 0.71 | RXFP1 (0.46) | NPSR1ALDH1A1TSHRKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013280-A | Compound for regulating 15-PGDH activity and preparation method thereof | 赛诺哈勃药业（成都）有限公司 | 2024-11-22 | — | — | CN | disclosed |