Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31156502 | 0.71 | NPSR1 (0.57) | RXFP1PPARGNCOR2ALDH1A1NPSR1 | |
| SCHEMBL8382994 | 0.71 | NPSR1 (0.59) | PPARGALDH1A1NPSR1L3MBTL1KMT2A | |
| SCHEMBL4988245 | 0.70 | ALDH1A1 (0.47) | RXFP1PPARGNCOR2ALDH1A1NPSR1 | |
| SCHEMBL8380313 | 0.69 | HPGD (0.65) | RXFP1PPARGNCOR2ALDH1A1NPSR1 | |
| SCHEMBL4787157 | 0.68 | ALDH1A1 (0.45) | RXFP1PPARGNCOR2ALDH1A1NPSR1 | |
| SCHEMBL8384543 | 0.68 | NPSR1 (0.53) | RXFP1ALDH1A1NPSR1L3MBTL1KMT2A | |
| SCHEMBL14070104 | 0.66 | NPSR1 (0.45) | RXFP1PPARGNCOR2ALDH1A1NPSR1 | |
| SCHEMBL8379758 | 0.66 | KMT2A (0.43) | RXFP1PPARGNCOR2ALDH1A1NPSR1 | |
| SCHEMBL6442594 | 0.66 | ADORA1 (0.71) | RXFP1ADORA2AADORA1CYP1A2CYP2C9 | |
| SCHEMBL4785941 | 0.65 | FLT3 (0.48) | ALDH1A1NPSR1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008110891-A2 | NEW HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED, (IN) | 2008-09-18 | — | — | WO | disclosed |