Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31156487 | 0.82 | KDM4E (0.67) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27491238 | 0.82 | MAPT (0.56) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27490182 | 0.81 | MAPT (0.65) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4427626 | 0.81 | BRAF (0.54) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27551749 | 0.80 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27557179 | 0.79 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31156462 | 0.79 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31156513 | 0.79 | ALDH1A1 (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6218448 | 0.77 | LHCGR (0.57) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27490906 | 0.77 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013280-A | Compound for regulating 15-PGDH activity and preparation method thereof | 赛诺哈勃药业（成都）有限公司 | 2024-11-22 | — | — | CN | disclosed |