SCHEMBL3115681

SCHEMBL3115681

CN(C)c1nc(N(C)CO)nc(N(CO)CO)n1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
CYP1A2 P05177 1/20 0.48
THRB P10828 1/20 0.48
BLM P54132 1/20 0.48
CREBBP Q92793 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ALDH1A1 P00352 5/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
KDM4E B2RXH2 1/20 0.38
SLC29A1 Q99808 1/20 0.37
POLB P06746 2/20 0.35
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22058984 0.91 LMNA (0.58) LMNACYP1A2THRBBLMCREBBP
SCHEMBL1309901 0.91 LMNA (0.58) LMNACYP1A2THRBBLMCREBBP
SCHEMBL1817804 0.91 LMNA (0.58) LMNACYP1A2THRBBLMCREBBP
SCHEMBL19272104 0.91 LMNA (0.58) LMNACYP1A2THRBBLMCREBBP
SCHEMBL25739494 0.88 LMNA (0.44) LMNACYP1A2THRBBLMCREBBP
Trimelamol SCHEMBL1419460 0.83 LMNA (0.42) LMNACYP1A2THRBBLMCREBBP
SCHEMBL11294618 0.83 MAPT (0.39) SLC29A1
SCHEMBL27649444 0.81 LMNA (0.46) LMNACYP1A2THRBBLMCREBBP
SCHEMBL11041809 0.80 LMNA (0.33) LMNAALDH1A1SLC29A1POLB
SCHEMBL62379 0.80 SLC29A1 (0.30) SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12521697-B2 Cement plug composition for application to a ceramic honeycomb body and method of forming plugged ceramic honeycomb body with the same CORNING INCORPORATED (US) 2026-01-13 US claimed
US-20230148341-A1 CEMENT PLUG COMPOSITION FOR APPLICATION TO A CERAMIC HONEYCOMB BODY AND METHOD OF FORMING PLUGGED CERAMIC HONEYCOMB BODY WITH THE SAME CORNING INCORPORATED 2023-05-11 US claimed
CN-115667177-A Binder plugging compositions for application to ceramic honeycomb bodies and methods of forming plugged ceramic honeycomb bodies therewith 康宁股份有限公司 2023-01-31 CN claimed
EP-4121400-A1 CEMENT PLUG COMPOSITION FOR APPLICATION TO A CERAMIC HONEYCOMB BODY AND METHOD OF FORMING PLUGGED CERAMIC HONEYCOMB BODY WITH THE SAME Corning Incorporated (US) 2023-01-25 EP claimed
WO-2021188348-A1 CEMENT PLUG COMPOSITION FOR APPLICATION TO A CERAMIC HONEYCOMB BODY AND METHOD OF FORMING PLUGGED CERAMIC HONEYCOMB BODY WITH THE SAME CORNING INCORPORATED (US) 2021-09-23 WO claimed
US-12521697-B2 Cement plug composition for application to a ceramic honeycomb body and method of forming plugged ceramic honeycomb body with the same CORNING INCORPORATED (US) 2026-01-13 US disclosed
US-20230148341-A1 CEMENT PLUG COMPOSITION FOR APPLICATION TO A CERAMIC HONEYCOMB BODY AND METHOD OF FORMING PLUGGED CERAMIC HONEYCOMB BODY WITH THE SAME CORNING INCORPORATED 2023-05-11 US disclosed
CN-115667177-A Binder plugging compositions for application to ceramic honeycomb bodies and methods of forming plugged ceramic honeycomb bodies therewith 康宁股份有限公司 2023-01-31 CN disclosed
EP-4121400-A1 CEMENT PLUG COMPOSITION FOR APPLICATION TO A CERAMIC HONEYCOMB BODY AND METHOD OF FORMING PLUGGED CERAMIC HONEYCOMB BODY WITH THE SAME Corning Incorporated (US) 2023-01-25 EP disclosed
WO-2021188348-A1 CEMENT PLUG COMPOSITION FOR APPLICATION TO A CERAMIC HONEYCOMB BODY AND METHOD OF FORMING PLUGGED CERAMIC HONEYCOMB BODY WITH THE SAME CORNING INCORPORATED (US) 2021-09-23 WO disclosed
US-20190011433-A1 CELL CO-CULTURE SYSTEMS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2019-01-10 US disclosed
US-20130274142-A1 Cell Co-Culture Systems and Uses Thereof DANA-FARBER CANCER INSTITUTE, INC. 2013-10-17 US disclosed
US-20050227266-A1 Biomarker:compound correlations in cancer diagnosis and therapy APPLIED GENOMICS, INC. 2005-10-13 US disclosed
EP-0882037-B1 ARTEMISININ DIMER COMPOUNDS HAVING ANTICANCER ACTIVITY HAUSER CHEMICAL RES INC (US) 2001-09-12 EP disclosed
EP-0882037-A4 ARTEMISININ DIMER COMPOUNDS HAVING ANTICANCER ACTIVITY HAUSER CHEMICAL RES INC (US) 2000-01-19 EP disclosed
EP-0882037-A1 ARTEMISININ DIMER COMPOUNDS HAVING ANTICANCER ACTIVITY HAUSER CHEMICAL RESEARCH, INC. (US) 1998-12-09 EP disclosed
WO-1997001548-A1 ARTEMISININ DIMER COMPOUNDS HAVING ANTICANCER ACTIVITY HAUSER CHEMICAL RESEARCH, INC. (US) 1997-01-16 WO disclosed
US-4190417-A TRANSFERRING DYE FROM SOFTENED FOAM SHEET MOBAY CHEMICAL CORPORATION (US) 1980-02-26 US disclosed
US-4072466-A Cellulosic textile treated with low formaldehyde fully etherified methylolated melamine with urea-formaldehyde-glyoxal AMERICAN CYANAMID COMPANY (US) 1978-02-07 US disclosed
US-4039496-A Low formaldehyde fully etherified methylolated melamine with urea-formaldehyde-glyoxal as textile resin AMERICAN CYANAMID COMPANY (US) 1977-08-02 US disclosed