SCHEMBL11041809

SCHEMBL11041809

CNc1nc(N(C)CO)nc(N(CO)CO)n1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
POLB P06746 1/20 0.32
ALDH1A1 P00352 1/20 0.31
SLC29A1 Q99808 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL1979613 0.95 CA12 (0.33) LMNACA12CA1CA2CA9
SCHEMBL8630204 0.92 LMNA (0.36) LMNACA12CA1CA2CA9
SCHEMBL11774949 0.90 ALDH1A1 (0.35) LMNAPOLBALDH1A1SLC29A1
SCHEMBL9053288 0.88 LMNA (0.36) LMNACA12CA1CA2CA9
SCHEMBL3115681 0.80 LMNA (0.48) LMNAPOLBALDH1A1SLC29A1
SCHEMBL12869603 0.80 ALDH1A1 (0.33) LMNACA12CA1CA2CA9
SCHEMBL11294618 0.77 MAPT (0.39) SLC29A1
Trimelamol SCHEMBL1419460 0.77 LMNA (0.42) LMNACA12CA1CA2CA9
SCHEMBL6274301 0.75 GAA (0.38) CA12CA1CA2CA9POLB
SCHEMBL62379 0.74 SLC29A1 (0.30) SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4427754-A PAPER BASE WITH PRECOAT OF WATER COLUBLE POLYMER AND INORGANIC PIGMENT IN RESIN, PHOTOCONDUCTIVITY LAYER OF ZINC OXIDE IN BINDER, AND BACKINGS MITSUBISHI PAPER MILLS, LTD. (JP) 1984-01-24 US disclosed
EP-0012587-B1 THERMO-SENSITIVE MULTI-COLOR RECORDING MATERIAL AND PROCESS FOR PREPARATION THEREOF Ricoh Company, Ltd (JP) 1983-05-25 EP disclosed
US-4311750-A DISCOLORING LAYER OF CROSSLINKING RESIN DISPOSED BETWEEN COLORING LAYERS RICOH COMPANY LIMITED (JP) 1982-01-19 US disclosed
US-3955977-A GRAPHIC DISPLAYS XEROX CORPORATION (US) 1976-05-11 US disclosed