Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31157409 | 0.92 | MAPT (0.42) | GAAHTTNPSR1ENPP2KDM4E | |
| SCHEMBL31157518 | 0.90 | GAA (0.43) | GAAHTTLMNACYP2C9ATP6V1B2 | |
| SCHEMBL31157410 | 0.89 | NPSR1 (0.38) | GAAHTTLMNACYP2C9ATP6V1B2 | |
| SCHEMBL31157532 | 0.89 | LMNA (0.43) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL31157378 | 0.88 | CHRM1 (0.48) | LMNAENPP2KDM4ECHRM1TSHR | |
| SCHEMBL31157485 | 0.88 | MAPT (0.43) | GAALMNAENPP2CNR1CNR2 | |
| SCHEMBL31157414 | 0.88 | ATM (0.43) | GAAHTTLMNACYP2C9ATP6V1B2 | |
| SCHEMBL31157592 | 0.87 | LMNA (0.37) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL31157489 | 0.85 | CSF1R (0.38) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL31157568 | 0.85 | KDM4E (0.45) | GAAHTTLMNACYP2C9ATP6V1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376100-A1 | PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1, 4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES | Redona Therapeutics, Inc. | 2024-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376100-A1 | PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1, 4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES | PAPSS1, OTUD7B, BRD7 | GAA 2528/4885HTT 3849/4885LMNA 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.