Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.56 |
| ▸ | NPY4R | P50391 | 6/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.44 |
| ▸ | NPY1R | P25929 | 4/20 | 0.44 |
| ▸ | NPY2R | P49146 | 2/20 | 0.44 |
| ▸ | GLP1R | P43220 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | GIPR | P48546 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | NMT2 | O60551 | 2/20 | 0.43 |
| ▸ | NMT1 | P30419 | 2/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31157753 | 0.96 | TLR2 (0.49) | TLR2NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL20827746 | 0.92 | NPY4R (0.50) | TLR2NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL31157714 | 0.92 | NPY5R (0.51) | TLR2NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL31157731 | 0.88 | SIRT5 (0.51) | TLR2RXFP1IL23R | |
| SCHEMBL30463240 | 0.88 | SIRT5 (0.51) | TLR2RXFP1IL23R | |
| SCHEMBL31157691 | 0.88 | SIRT5 (0.51) | TLR2RXFP1IL23R | |
| SCHEMBL30463245 | 0.88 | SIRT5 (0.51) | TLR2RXFP1IL23R | |
| SCHEMBL31157710 | 0.87 | NPY4R (0.44) | TLR2NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL20827674 | 0.87 | NPY4R (0.45) | TLR2NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL13354428 | 0.87 | TLR2 (0.57) | TLR2NPY4RNPY5RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548510-B1 | COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES | LUBRIZOL ADVANCED MAT INC (US) | 2024-10-02 | — | — | EP | disclosed |