Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.42 |
| ▸ | ALKBH1 | Q13686 | 3/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 7/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31160268 | 0.92 | SIRT2 (0.46) | SIRT2SIRT3SIRT1 | |
| SCHEMBL5782201 | 0.79 | ABCB1 (0.43) | MEN1KMT2AHSD17B10SMN1; SMN2TP53 | |
| SCHEMBL31160258 | 0.77 | SIRT2 (0.51) | MEN1KMT2AHTTGFERHSD17B10 | |
| SCHEMBL31385508 | 0.76 | MAPK1 (0.33) | SIRT2SIRT3SIRT1 | |
| SCHEMBL30822583 | 0.75 | MEN1 (0.70) | MEN1KMT2AHTTGFERHSD17B10 | |
| SCHEMBL1201866 | 0.75 | MEN1 (0.70) | MEN1KMT2AHTTGFERHSD17B10 | |
| SCHEMBL6172243 | 0.75 | MEN1 (0.38) | MEN1KMT2AHTTHSD17B10MRGPRX4 | |
| SCHEMBL2197204 | 0.74 | MEN1 (0.68) | MEN1KMT2AHTTGFERHSD17B10 | |
| SCHEMBL5106543 | 0.74 | CYP4F2 (0.42) | MEN1KMT2ARAB9ASMN1; SMN2PKM | |
| SCHEMBL6170674 | 0.73 | HIF1A (0.44) | MEN1KMT2AMRGPRX4RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024199069-A1 | POLYARYL-CONTAINING MACROCYCLIC COMPOUND AND USE THEREOF | 浙江养生堂天然药物研究所有限公司 | 2024-10-03 | — | — | WO | disclosed |