Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31124766 | 0.91 | TSHR (0.35) | SMN1; SMN2TSHRHTTPPARGPPARA | |
| SCHEMBL21817202 | 0.86 | MRGPRX4 (0.38) | MEN1KMT2AMRGPRX4SMN1; SMN2RXRA | |
| SCHEMBL6170674 | 0.85 | HIF1A (0.44) | MEN1KMT2AMRGPRX4TSHRNPC1 | |
| SCHEMBL16818604 | 0.84 | TACR1 (0.34) | MEN1KMT2AMRGPRX4SMN1; SMN2TSHR | |
| SCHEMBL6170850 | 0.84 | UNG (0.38) | MEN1KMT2AMRGPRX4RXRARXRB | |
| SCHEMBL8024443 | 0.82 | MRGPRX4 (0.38) | MRGPRX4SMN1; SMN2TSHRNPC1TP53 | |
| SCHEMBL9342265 | 0.82 | RXRA (0.51) | SMN1; SMN2RXRARXRBRXRGNPC1 | |
| SCHEMBL21817599 | 0.82 | MRGPRX4 (0.35) | MEN1KMT2AMRGPRX4 | |
| SCHEMBL5106543 | 0.81 | CYP4F2 (0.42) | MEN1KMT2ASMN1; SMN2TSHRMAPT | |
| SCHEMBL2745018 | 0.81 | PPARG (0.41) | KMT2ATSHRRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192127-B1 | SUBSTITUTED BENZAMIDE INHIBITORS OF RHINOVIRUS 3C PROTEASE | AGOURON PHARMA (US) | 2005-03-30 | — | — | EP | disclosed |
| US-6369226-B1 | ENZYME INHIBITORS | AGOURON PHARMACEUTICALS, INC. | 2002-04-09 | — | — | US | disclosed |