Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3115823 | 1.00 | RAB9A (0.45) | RAB9AHRH3SPHK2PDK2POLB | |
| SCHEMBL3119266 | 0.89 | RAB9A (0.45) | RAB9AHRH3SPHK2PDK2POLB | |
| SCHEMBL1266849 | 0.86 | HRH3 (0.39) | RAB9AHRH3PDK2POLBDPP4 | |
| SCHEMBL1267138 | 0.86 | HRH3 (0.39) | RAB9AHRH3SPHK2PDK2POLB | |
| SCHEMBL3107145 | 0.84 | RAB9A (0.33) | RAB9AHRH3HCRTR1HCRTR2 | |
| SCHEMBL1266874 | 0.83 | HRH3 (0.41) | RAB9AHRH3SPHK2PDK2POLB | |
| SCHEMBL1265782 | 0.82 | RAB9A (0.38) | RAB9AHRH3SPHK2POLBL3MBTL1 | |
| SCHEMBL3116932 | 0.81 | RAB9A (0.42) | RAB9AHRH3RIPK1TRPV1TYK2 | |
| SCHEMBL3120948 | 0.81 | RAB9A (0.42) | RAB9AHRH3RIPK1TRPV1TYK2 | |
| SCHEMBL3117310 | 0.80 | RAB9A (0.42) | RAB9AHRH3RIPK1TRPV1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179185-A1 | Novel Aminothienopyridinone Derivatives Processes for Preparing Them and Pharmaceutical Compositions Thereof | UCB PHARMA, S.A. (BE) | 2010-07-15 | — | — | US | claimed |
| US-20100179185-A1 | Novel Aminothienopyridinone Derivatives Processes for Preparing Them and Pharmaceutical Compositions Thereof | UCB PHARMA, S.A. (BE) | 2010-07-15 | — | — | US | disclosed |
| EP-2099805-A2 | NOVEL AMINOTHIENOPYRIDINONE DERIVATIVES PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS THEREOF | UCB Pharma S.A. (BE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008064829-A2 | NOVEL AMINOTHIENOPYRIDINONE DERIVATIVES PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS THEREOF | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179185-A1 | Novel Aminothienopyridinone Derivatives Processes for Preparing Them and Pharmaceutical Compositions Thereof | AASDHPPT, PTMS, TPMT | RAB9A 596/4885HRH3 1649/4885SPHK2 2729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.