Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16653309 | 0.90 | MAPT (0.50) | SIGMAR1MAPTCCR3ALDH1A1POLB | |
| SCHEMBL12059418 | 0.87 | BCHE (0.66) | POLBKMT2ADRD2 | |
| SCHEMBL5276400 | 0.87 | EPHX2 (0.59) | SIGMAR1CCR3HTR1ADRD2HTR2A | |
| SCHEMBL27808768 | 0.82 | MAPT (0.49) | CA1CA2CA9MAPTHTT | |
| SCHEMBL8016039 | 0.82 | CCR3 (0.60) | SIGMAR1CCR3HTR2A | |
| SCHEMBL7801292 | 0.80 | ACHE (0.59) | SIGMAR1LMNA | |
| SCHEMBL5870720 | 0.78 | LTA4H (0.52) | MAPTHTTALDH1A1POLBLMNA | |
| SCHEMBL29086653 | 0.78 | KLK7 (0.72) | MAPTHTTALDH1A1KMT2ARAB9A | |
| SCHEMBL29381887 | 0.78 | CCR3 (0.75) | CCR3 | |
| SCHEMBL5276763 | 0.78 | DCUN1D1 (0.60) | MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033540-A1 | CRYSTALLINE FORMS OF FENTANYL ALKALOID | MALLINCKRODT INC. (US) | 2010-03-25 | — | — | WO | claimed |