SCHEMBL31163110

SCHEMBL31163110

Cc1cnc(Nc2ccc(C(=O)Nc3ccc(N4CCN(C)CC4)cc3)cc2)nc1Nc1ccc(N2CCN(C)CC2)cc1

nearest known ligand 0.79

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 19/20 0.79
JAK2 O60674 1/20 0.63
FLT3 P36888 1/20 0.63
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
JAK1 P23458 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31163120 0.90 BRD4 (0.75) BRD4JAK2FLT3
SCHEMBL31163118 0.89 BRD4 (0.67) BRD4JAK2FLT3JAK1
SCHEMBL17526180 0.88 BRD4 (1.00) BRD4JAK2FLT3
SCHEMBL28980990 0.87 SRC (0.69) BRD4JAK2FLT3
SCHEMBL17526046 0.85 BRD4 (1.00) BRD4JAK2FLT3NPC1RAB9A
SCHEMBL31163153 0.85 BRD4 (0.66) BRD4JAK2FLT3
SCHEMBL31163086 0.85 BRD4 (0.85) BRD4JAK2FLT3JAK1
SCHEMBL31163142 0.84 BRD4 (0.63) BRD4JAK2FLT3JAK1
SCHEMBL265060 0.83 BRD4 (0.82) BRD4JAK2FLT3JAK1
SCHEMBL31163056 0.83 BRD4 (0.76) BRD4JAK2FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673149-A1 NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA Trustlife Global Inc. (US) 2026-01-07 EP disclosed
WO-2024179699-A1 NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA BASH BIOTECH INC. (US) 2024-09-06 WO disclosed