SCHEMBL31163699

SCHEMBL31163699

CCc1ccc(COC[C@H](F)CCCCN2C[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)C2)cc1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GUSB P08236 2/20 0.43
▸ UGCG Q16739 16/20 0.39
▸ GBA2 Q9HCG7 16/20 0.39
▸ GBA1 P04062 15/20 0.39
▸ GLB1 P16278 1/20 0.38
▸ LCT P09848 2/20 0.38
▸ SI P14410 2/20 0.38
▸ MGAM O43451 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31163689 1.00 GUSB (0.43) GUSBUGCGGBA2GBA1GLB1
SCHEMBL31163877 0.91 GUSB (0.44) GUSBUGCGGBA2GBA1GLB1
SCHEMBL31163690 0.91 GBA1 (0.48) GUSBUGCGGBA2GBA1LCT
SCHEMBL31163686 0.91 GBA1 (0.48) GUSBUGCGGBA2GBA1LCT
SCHEMBL31163925 0.90 GUSB (0.46) GUSBUGCGGBA2GBA1GLB1
SCHEMBL31163917 0.89 UGCG (0.49) GUSBUGCGGBA2GBA1LCT
SCHEMBL31163810 0.89 GUSB (0.38) GUSBUGCGGBA2GBA1LCT
SCHEMBL31163687 0.88 UGCG (0.48) GUSBUGCGGBA2GBA1LCT
SCHEMBL31163701 0.88 UGCG (0.48) GUSBUGCGGBA2GBA1LCT
SCHEMBL31163863 0.88 GBA1 (0.49) UGCGGBA2GBA1LCTSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673215-A1 GBA1 AND GCS DUAL MODULATOR ONO Pharmaceutical Co., Ltd. (JP) 2026-01-07 — — EP claimed
WO-2024179491-A1 GBA1 AND GCS DUAL MODULATOR ONO PHARMACEUTICAL CO., LTD. (JP) 2024-09-06 — — WO claimed
WO-2024179491-A1 GBA1 AND GCS DUAL MODULATOR ONO PHARMACEUTICAL CO., LTD. (JP) 2024-09-06 — — WO disclosed
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