SCHEMBL31163877 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	GUSB	P08236	2/20	0.44

▸	GLB1	P16278	1/20	0.40

▸	GBA1	P04062	11/20	0.38

▸	UGCG	Q16739	10/20	0.38

▸	GBA2	Q9HCG7	10/20	0.38

▸	PYGL	P06737	1/20	0.38

▸	GAA	P10253	3/20	0.37

▸	LCT	P09848	2/20	0.36

▸	SI	P14410	2/20	0.36

▸	MGAM	O43451	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31163925	0.94	GUSB (0.46)	GUSBGLB1GBA1UGCGGBA2
SCHEMBL31163689	0.91	GUSB (0.43)	GUSBGLB1GBA1UGCGGBA2
SCHEMBL31163699	0.91	GUSB (0.43)	GUSBGLB1GBA1UGCGGBA2
SCHEMBL31163686	0.89	GBA1 (0.48)	GUSBGBA1UGCGGBA2GAA
SCHEMBL31163690	0.89	GBA1 (0.48)	GUSBGBA1UGCGGBA2GAA
SCHEMBL31163917	0.87	UGCG (0.49)	GUSBGBA1UGCGGBA2GAA
SCHEMBL31163810	0.87	GUSB (0.38)	GUSBGBA1UGCGGBA2LCT
SCHEMBL31163701	0.86	UGCG (0.48)	GUSBGBA1UGCGGBA2GAA
SCHEMBL31163687	0.86	UGCG (0.48)	GUSBGBA1UGCGGBA2GAA
SCHEMBL31163863	0.86	GBA1 (0.49)	GBA1UGCGGBA2PYGLGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024179491-A1	GBA1 AND GCS DUAL MODULATOR	ONO PHARMACEUTICAL CO., LTD. (JP)	2024-09-06	—	—	WO	disclosed