Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | GBA1 | P04062 | 5/20 | 0.41 |
| ▸ | UGCG | Q16739 | 5/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31163849 | 0.90 | SMN1; SMN2 (0.34) | LMNAGBA1UGCGGBA2ALDH1A1 | |
| SCHEMBL31163900 | 0.90 | KDM4E (0.35) | LMNAGBA1UGCGGBA2MAPT | |
| SCHEMBL31163825 | 0.86 | UGCG (0.53) | LMNAGBA1UGCGGBA2 | |
| SCHEMBL31163903 | 0.86 | UGCG (0.53) | LMNAGBA1UGCGGBA2 | |
| SCHEMBL31163840 | 0.85 | GBA1 (0.31) | GBA1UGCGGBA2 | |
| SCHEMBL31163844 | 0.82 | UGCG (0.43) | LMNAGBA1UGCGGBA2ALDH1A1 | |
| SCHEMBL31163682 | 0.79 | GBA1 (0.39) | LMNAGBA1UGCGGBA2ALDH1A1 | |
| SCHEMBL31163694 | 0.79 | GBA1 (0.39) | LMNAGBA1UGCGGBA2ALDH1A1 | |
| SCHEMBL31163683 | 0.76 | GBA2 (0.43) | GBA1UGCGGBA2 | |
| SCHEMBL31163931 | 0.76 | UGCG (0.53) | LMNAGBA1UGCGGBA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024179491-A1 | GBA1 AND GCS DUAL MODULATOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-09-06 | — | — | WO | disclosed |