Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 9/20 | 0.35 |
| ▸ | UGCG | Q16739 | 9/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 9/20 | 0.35 |
| ▸ | LCT | P09848 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31163893 | 0.90 | LMNA (0.41) | GBA1UGCGGBA2LMNATP53 | |
| SCHEMBL31163849 | 0.88 | SMN1; SMN2 (0.34) | KDM4EGBA1UGCGGBA2SMN1; SMN2 | |
| SCHEMBL31163875 | 0.87 | UGCG (0.45) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163840 | 0.86 | GBA1 (0.31) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163908 | 0.83 | UGCG (0.39) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163866 | 0.80 | KDM4E (0.34) | KDM4ENPC1RAB9AGBA1UGCG | |
| Hydrochloric Acid SCHEMBL31163788 | 0.78 | UGCG (0.42) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163772 | 0.78 | GBA1 (0.42) | KDM4EGBA1UGCGGBA2LCT | |
| SCHEMBL31163888 | 0.77 | GBA2 (0.42) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163825 | 0.76 | UGCG (0.53) | GBA1UGCGGBA2LCTMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024179491-A1 | GBA1 AND GCS DUAL MODULATOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-09-06 | — | — | WO | disclosed |